Chronic hypoxia has differential effects on constitutive and antigen-stimulated immune function in Atlantic salmon (<i>Salmo salar</i>).

ABSTRACT: Chronic hypoxia events are a common occurrence in Atlantic salmon (Salmo salar) sea-cages, especially during the summer, and their frequency and severity are predicted to increase with climate change. Although hypoxia is considered a very important fish health and welfare issue by the aquaculture industry, few studies have investigated the impact of chronic hypoxia on the fish immune system and its response to pathogen exposure. We exposed post-smolt Atlantic salmon to hypoxia (40% air sat.) for 6 weeks. Thereafter, we sampled fish prior to (i.e., at Time 0, to assess constitutive immune function), and after they were intraperitoneally injected with PBS (phosphate buffered saline) or formalin-killed Aeromonas salmonicida. We measured several innate immune parameters including

SUBMITTER: Rojas I 

PROVIDER: S-EPMC11880259 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature