Regulation of lanthanide supramolecular nanoreactors via a bimetallic cluster cutting strategy to boost aza-Darzens reactions.

ABSTRACT: Supramolecular nanoreactor as artificial mimetic enzyme is attracting a growing interest due to fine-tuned cavity and host-guest molecular recognition. Here, we design three 3d-4f metallo-supramolecular nanocages with different cavity sizes and active sites (Zn₂Er₄L¹₄, Zn₄Er₆L²₆, and Zn₂Er₈L³₈) based on a "bimetallic cluster cutting" strategy. Three nanocages exhibit a differential catalysis for the three-component aza-Darzens reaction without another additive, and only Zn₂Er₈L³₈ with the largest cavity and the most lanthanides centers has excellent catalytic conversion for monosubstituted and disubstituted N-aryl az

SUBMITTER: Li J 

PROVIDER: S-EPMC11880432 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature