Palatal canine impaction is not associated with third molar agenesis.

ABSTRACT:

Background/objectives

Third molar agenesis and palatally impacted canines (PICs) are two independent dental phenotypes with different developmental backgrounds. Isolated reports indicate a common genetic origin for both, however, current data is inconsistent. The aim of this study was to investigate the presence of third molar agenesis in individuals with PICs, compared to individuals without PICs.

Materials/methods

This retrospective case-control study comprised 310 individuals (188 females and 122 males), half of whom presented with unilateral or bilateral PICs. Individuals with other dental anomalies of known genetic origin were excluded. The association between PICs and third molar agenesis was assessed using four regression models, with PIC as the dependent variable and

SUBMITTER: Papadopoulou CI 

PROVIDER: S-EPMC11880766 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature