Long-term outcomes of bilateral salpingo-oophorectomy in women with personal history of breast cancer.

ABSTRACT:

Objectives

To investigate the association between bilateral salpingo-oophorectomy (BSO) and long-term health outcomes in women with a personal history of breast cancer.

Methods and analysis

We used data on women diagnosed with invasive breast cancer between 1995 and 2019 from the National Cancer Registration Dataset (NCRD) in England. The data were linked to the Hospital Episode Statistics-Admitted Patient Care dataset to identify BSO delivery. Long-term health outcomes were selected from both datasets. Multivariable Cox regression was used to examine the associations, with BSO modelled as a time-dependent covariate. The associations were investigated separately by age at BSO.

Results

We identified 568 883 women, 23 401 of whom had BSO after the breast cancer diagnosi

SUBMITTER: Hassan H 

PROVIDER: S-EPMC11880784 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature