Elevated levels of C-reactive protein and pig major acute phase protein in lame gestating sows.

ABSTRACT:

Introduction

Lameness is a common clinical issue in gestating sows and a leading cause for early culling and antibiotic treatment. Diagnostic tools are limited, but acute acute phase proteins (APPs) could offer a fast and minimally invasive method for optimizing treatment. The aim of this study was to investigate whether APP level measurements can be used as a diagnostic tool, and to identify which major acute phase proteins are elevated in lame gestating sows.

Methods

To determine this, blood samples were collected from the jugular vein of 50 lame and 50 clinically healthy gestating sows from 12 conventional herds. The samples were analyzed for C-reactive protein (CRP), haptoglobin, serum amyloid A, and pig major acute phase protein (Pig-MAP) levels using sandwich ELISA.

SUBMITTER: Jakobsen N 

PROVIDER: S-EPMC11880936 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature