Electronic Sepsis Screening Among Patients Admitted to Hospital Wards: A Stepped-Wedge Cluster Randomized Trial.

ABSTRACT:

Importance

Sepsis screening is recommended among hospitalized patients but is supported by limited evidence of effectiveness.

Objective

To evaluate the effect of electronic sepsis screening, compared with no screening, on mortality among hospitalized ward patients.

Design, setting, and participants

In a stepped-wedge, cluster randomized trial at 5 hospitals in Saudi Arabia, 45 wards (clusters) were randomized into 9 sequences, 5 wards each, to have sepsis screening implemented at 2-month periods. The study was conducted between October 1, 2019, and July 31, 2021, with follow-up through October 29, 2021.

Intervention

An electronic alert, based on the quick Sequential Organ Failure Assessment score, was implemented in the electronic medical record in a silent mod

SUBMITTER: Arabi YM 

PROVIDER: S-EPMC11880955 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature