New Fluorescent Chemodosimetric Mechanism for Selective Recognition of Selenocysteine by Dansyl-Appended Ruthenium Nitrosyl Complexes.

ABSTRACT: Selenocysteine (Sec) is a biologically essential amino acid that serves as a crucial component in selenoproteins that play a key role in various cellular functions. Thus, developing a reliable and rapid method for detecting Sec in physiological media is of paramount importance. This report introduces for the first time a novel fluorescent chemodosimetric mechanism for the selective recognition of Sec using dansyl-appended ruthenium nitrosyl complexes. These complexes consist of a tetradentate ligand featuring a π-extended system (L = N,N'-bis(2-hydroxy-1-naphthylidene)-1,2-phenylenediamine) and a monodentate ligand derived from the conjugated dansyl group, which acts as a strong fluorescent signaling unit (ID = dansyl-imidazole, BD = dansyl-benzimidazole)

SUBMITTER: Bazany-Rodriguez IJ 

PROVIDER: S-EPMC11881044 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature