Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm.

ABSTRACT:

Rationale

The respiratory outcomes for adult survivors of preterm birth in the postsurfactant era are wide-ranging with prognostic factors, especially those encountered after the neonatal period, poorly understood.

Objectives

To obtain comprehensive 'peak' lung health data from survivors of very preterm birth and identify neonatal and life-course risk factors for poorer respiratory outcomes in adulthood.

Methods

127 participants born ≤32 weeks gestation (64%, n=81 with bronchopulmonary dysplasia (BPD), initially recruited according to a 2 with-BPD:1 without-BPD strategy), and 41 term-born controls completed a lung health assessment at 16-23 years, including lung function, imaging and symptom review. Risk factors assessed against poor lung health included neonatal trea

SUBMITTER: Smith EF 

PROVIDER: S-EPMC11881051 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature