Impact of probiotic supplements on behavioural and gastrointestinal symptoms in children with autism spectrum disorder: A randomised controlled trial.

ABSTRACT:

Objective

To investigate whether probiotic supplementation can improve behavioural and gastrointestinal (GI) symptoms in children with autism spectrum disorder (ASD) aged 2-9 years and further explore the correlation between these symptoms.

Design

Single-blinded, randomised, placebo-controlled study.

Setting

Five developmental paediatric outpatient clinics of 'Continua Kids'.

Patients

Children aged 2-9 years diagnosed with ASD along with their caregivers.

Interventions

Probiotic or placebo sachet reconstituted in 50 mL of lukewarm milk/water, taken two times per day for 3 months.

Main outcome measures

Change in behavioural (measured by Social Responsiveness Scale-2 (SRS-2) and Aberrant Behaviour Checklist-2 (ABC-2) tools) and GI (measured by GI Se

SUBMITTER: Narula Khanna H 

PROVIDER: S-EPMC11881170 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature