Investigation and analysis of female HPV infection and genotype distribution in Xuhui District, Shanghai.

ABSTRACT:

Objective

In China, Cervical cancer is one of the common malignant tumors in females, and high-risk human papillomavirus (HR-HPV) infection is one of its main causative factors. However, human papillomavirus (HPV) infection rates may vary significantly among patients of different ages and HPV subtypes. This study aims to provide insights into developing cervical cancer screening strategies and selecting HPV vaccine antigen targets in the area.

Methods

A retrospective analysis was conducted on the HPV testing results of 47,423 women from January 2017 to April 2023 at the Clinical Laboratory of the Eighth People's Hospital in Shanghai. HPV DNA genotyping was performed using real-time quantitative polymerase chain reaction (PCR) in the molecular laboratory. Statistical analysis

SUBMITTER: Liu H 

PROVIDER: S-EPMC11881386 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature