Is the oral pathogen, Porphyromona gingivalis, associated to colorectal cancer?: a systematic review.

ABSTRACT:

Background

The association between the oral pathogen Porphyromonas gingivalis (PG) and the gut microbiota in colorectal cancer (CRC) patients has been explored with inconsistent results. This study aims to systematically assess this potential association.

Materials and methods

A systematic review was conducted across three databases (Pubmed, Embase and Web of Science) from inception up to January 2023 and updated until November 2024. Inclusion criteria were observational studies examining PG in the microbiota of adults with CRC compared to healthy controls. Exclusion criteria were studies without control group of healthy individuals, other designs or without full-text access. Two reviewers independently selected and extracted data following a pre-registered protocol. Disagre

SUBMITTER: Navarro-Sanchez A 

PROVIDER: S-EPMC11881450 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature