The interplay between epigenomic and transcriptomic variation during ecotype divergence in stickleback.

ABSTRACT:

Background

Populations colonizing contrasting environments are likely to undergo adaptive divergence and evolve ecotypes with locally adapted phenotypes. While diverse molecular mechanisms underlying ecotype divergence have been identified, less is known about their interplay and degree of divergence.

Results

Here we integrated epigenomic and transcriptomic data to explore the interactions among gene expression, alternative splicing, DNA methylation, and microRNA expression to gauge the extent to which patterns of divergence at the four molecular levels are aligned in a case of postglacial divergence between marine and freshwater ecotypes of nine-spined sticklebacks (Pungitius pungitius). Despite significant genome-wide associations between epigenomic and transcriptomic vari

SUBMITTER: Luo M 

PROVIDER: S-EPMC11881503 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature