Prevalence and mortality associated with multidrug-resistant infections in adult intensive care units in Argentina (PREV-AR).

ABSTRACT: Data from low and middle-income countries (LMICs) on multidrug-resistant microorganisms (MDROs) in intensive care units (ICUs) are scarce. Working in several ICUs in Argentina, we sought to estimate the prevalence and characteristics of MDRO infections and carbapenemase-producing Enterobacterales (CPE) colonization. Mortality associated with MDRO infection was also evaluated. The study was a 24-hour point prevalence study conducted in 164 adult ICUs in Argentina between 24 November and 28 November 2023. The main study outcome was in-ICU mortality and secondary outcomes included the prevalence of MDRO infections, the prevalence of CPE colonization (defined as CPE recovered from a rectal swab), and ICU length of stay (LoS). Mixed effects modeling was used to identify risk factors for in-ICU

SUBMITTER: Cornistein W 

PROVIDER: S-EPMC11881575 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature