Dementia prevalence and risk factors in people with and without HIV in Malawi: A medical record review.

ABSTRACT:

Background

Sub-Saharan Africa (SSA) is experiencing a rapid increase in its aging population, including people living with human immunodeficiency virus (HIV) (PLHIV). The purpose of this study was to determine the prevalence of dementia among PLHIV and people without HIV (POHIV) in Malawi.

Methods

We conducted a retrospective medical record review of 400 consecutive patients from a single tertiary health center (200 PLHIV from an HIV clinic and 200 POHIV from an outpatient clinic) in Lilongwe, Malawi.

Results

The overall rate of dementia was higher in PLHIV than that in POHIV (22% vs 10%; p = 1.4e). Older age, unknown employment or unemployed, and depression were significant risk factors for dementia for PLHIV, while older age and depression were significant among POH

SUBMITTER: Lee H 

PROVIDER: S-EPMC11881610 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature