Lung cancer screening with volume computed tomography is cost-effective in Greece.

ABSTRACT:

Objective

This study aimed to assess the cost-effectiveness of lung cancer screening (LCS) employing volume-based low-dose computed tomography (LDCT) in contrast to the absence of screening, targeting an asymptomatic high-risk population in Greece, leveraging the outcomes derived from the NELSON study, the largest European randomized control trial dedicated to LCS.

Methods

A validated model incorporating a decision tree and an integrated state-transition Markov model was used to simulate the identification, diagnosis, and treatments for a population at high risk of developing lung cancer, from a healthcare payer perspective. Screen-detected lung cancers, costs, life years (LYs), quality-adjusted life years (QALYs), and the incremental cost-effectiveness ratio (ICER) were pre

SUBMITTER: Pan X 

PROVIDER: S-EPMC11882067 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature