Long-Term Outcomes After CyberKnife Radiosurgery for Nonfunctioning Pituitary Adenomas.

ABSTRACT:

Background and objectives

Stereotactic radiosurgery (SRS) has been widely adopted as an important adjunctive treatment modality for managing nonfunctioning pituitary adenomas (NFPAs). However, current studies on the long-term effects of SRS on pituitary adenomas have been largely limited by small sample sizes and short follow-up periods. The aim of this study was to evaluate the long-term outcomes of SRS for NFPAs.

Methods

We conducted a retrospective review of 178 patients with NFPAs who received CyberKnife radiosurgery at a single institution between February 2008 and July 2021. Long-term outcomes of tumor control, new-onset hypopituitarism, and new visual disorders were assessed.

Results

During a median radiological follow-up of 49.7 months (range, 2.5-158.1 months

SUBMITTER: Wei N 

PROVIDER: S-EPMC11882279 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature