Branched-Chain Amino Acids Target miR-203a/fosb Axis to Promote Skeletal Muscle Growth in Common Carp (<i>Cyprinus carpio</i>).

ABSTRACT: Starvation is an environmental stress that cannot be ignored during the growth of aquatic animals. Amino acid composition and balance can influence the nutritional effects, regulating the anabolic metabolism and energy signaling in the organism. Among these, branched-chain amino acids (BCAAs), which are essential amino acids in fish, play vital roles in energy regulation and growth metabolism. In order to observe the recovery effect of BCAAs in sustained duration starvation of common carp, a 4-week starvation period was initiated, followed by a 4-week feeding period with different concentrations of compound BCAAs (leucine:isoleucine:valine = 2:1:1). The detection of skeletal muscle protein deposition, muscle proliferation and differentiation, and indicators related to muscle atrophy at the

SUBMITTER: Cao X 

PROVIDER: S-EPMC11882326 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature