Case report: Molecular characterization of adult atypical teratoid rhabdoid tumor and review of the literature.

ABSTRACT:

Background and importance

Atypical teratoid rhabdoid tumors (ATRTs) are typically aggressive pediatric tumors with a median survival of 11 months. Due to the paucity of cases in adults, the clinical behavior of these pathologies is not well understood. Here we present the case of a 41-year-old female patient with postoperative hyperprogression of a sellar ATRT and provide a detailed description of the molecular composition of this tumor, the protocol used to treat this patient, and the ultimate outcome of this patient.

Clinical presentation

The patient is a 41-year-old woman who presented with headaches and double vision. MRI revealed a sellar/suprasellar mass with involvement of bilateral cavernous sinuses. Following the quick symptom progression, resection of the tumor wit

SUBMITTER: Hernandez-Rovira MA 

PROVIDER: S-EPMC11882417 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature