Vascularised organoids: Recent advances and applications in cancer research.

ABSTRACT: Organoids are three-dimensional (3D) cellular models designed to replicate human tissues and organs while preserving their physiological complexity and functionality. Among these, vascularised organoids represent a groundbreaking advancement in 3D tissue engineering, incorporating vascular networks into engineered tissues to more accurately mimic the in vivo tumour microenvironment. These models offer significantly improved physiological relevance compared to conventional two-dimensional cultures or animal models, positioning them as invaluable tools in cancer research. Despite their potential, the rapid proliferation of techniques and materials for developing vascularised organoids presents challenges for researchers navigating this dynamic field. This systematic review provides a compreh

SUBMITTER: Zhou R 

PROVIDER: S-EPMC11882480 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature