Addressing uncertainty in hereditary colorectal cancer: the role of a regional expert multidisciplinary team meeting.

ABSTRACT: There is frequent uncertainty in both the precise quantification of risk, and the application of clinical interventions, designed to mitigate increased heritable colorectal cancer (CRC) susceptibility. We evaluated the role of a collaborative specialist multidisciplinary team meeting (MDM) for familial and hereditary CRC, led by the St Mark's Hospital Centre for Familial Intestinal Cancer specifically in supporting the clinical management of uncertainty. A retrospective thematic analysis of meeting outcomes from inception in June 2020 until March 2023 was performed. Descriptive statistics were employed to ascertain clinicopathological data, clinical queries and whether MDM recommendations were outside the scope of current guidelines. In total 260 cases were discussed from 13 regional insti

SUBMITTER: Varde A 

PROVIDER: S-EPMC11882607 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature