The Effects of Perioperative Corticosteroids on Postoperative Complications After Pancreatoduodenectomy: A Debated Topic of Systematic Review and Meta-analysis.

ABSTRACT:

Background

The intraoperative administration of corticosteroids has been shown to improve postoperative outcomes in patients undergoing surgery; however, the impact of corticosteroids on complications following pancreatoduodenectomy (PD) remains controversial.

Objective

This study aimed to evaluate the efficacy of perioperative corticosteroids on postoperative complications after PD.

Materials and methods

A comprehensive search was conducted using the PubMed, Embase, and Web of Science databases for studies published prior to 1 July 2024. Of 7418 articles identified, a total of 5 studies were eligible for inclusion in this meta-analysis. The primary outcome was incidence of postoperative major complications (PMCs), while the additional outcomes were incidences of post

SUBMITTER: Liu H 

PROVIDER: S-EPMC11882649 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature