Molecular characterization of the heterogeneity of satellite cell populations isolated from an individual Turkey pectoralis major muscle.

ABSTRACT: Satellite cells (SCs) are myogenic stem cells responsible for post hatch muscle growth and the regeneration of muscle fibers. Satellite cells are not a homogenous population of cells within a muscle and have variable rates of proliferation and differentiation even within a single fiber type muscle like the turkey pectoralis major muscle. In this study, the single satellite cell clones derived from the same turkey pectoralis major muscle with different proliferation rates were compared. The clones were classified as either fast-growing (early clone) or slow-growing (late clone) SCs. To thoroughly examine the molecular differences between these two groups, RNA sequencing was conducted to compare their transcriptomes following 72 h of proliferation. Principal Component Analysis confirmed that

SUBMITTER: Yu H 

PROVIDER: S-EPMC11882874 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature