Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study.

ABSTRACT:

Background

Statins are one of the most widely prescribed medicines in clinical practice. Their benefits have extended beyond cardiovascular applications to reduce serum uric acid levels. This study aims to investigate the relationship of hyperuricemia with the risk of all-cause mortality among individuals taking statins.

Method

A retrospective cohort study was performed using data from the National Health and Nutrition Examination Survey (NHANES) database between 2005 and 2018. The weighted Cox proportional hazards models were used to investigate the relationship between hyperuricemia and all cause-mortality.

Results

A total of 1,958 participants were enrolled for analysis. Of them 1,429 participants were with normal uric acid levels and 529 people were with hyperuric

SUBMITTER: Zhu B 

PROVIDER: S-EPMC11883159 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature