Cardiovascular risk prediction in hemodialysis patients using the triglyceride-glucose index: a multicenter prospective cohort study.

ABSTRACT:

Background

Triglyceride-glucose (TyG) index has recently been established as an indicator of insulin resistance and has predictive value for cardiovascular (CV) disease. However, the clinical significance of the TyG index in patients undergoing hemodialysis remains unknown.

Methods

We prospectively enrolled 759 patients undergoing maintenance hemodialysis. The participants were divided into tertiles based on their baseline TyG index. Echocardiographic parameters, vascular calcification scores, and several plasma biomarkers were obtained and compared using the TyG index.

Results

The TyG index was positively correlated with levels of circulating vascular pathologic markers, endostatin (ρ = 0.134, P = .025) and vascular adhesion protein-1 (ρ = 0.130,

SUBMITTER: Lee YH 

PROVIDER: S-EPMC11883225 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature