Mucositis Pain and Its Temporal Relationship to White Cell Count.

ABSTRACT:

Background

Children who have received chemotherapy and/or radiotherapy treatment resulting in neutropenia can suffer painful mucositis. We explored the relationship between pain score and white cell count in children with mucositis due to immunosuppression and assessed the influence of opioid and ketamine analgesia.

Methods

Children with mucositis nursed in the pediatric oncology and hematology ward were invited to partake in this observational study following referral to the pediatric pain service for intravenous analgesia. Pain scores, white cell count, neutrophil count, and analgesia requirements were recorded daily until intravenous analgesia was either stopped or transitioned to oral analgesia. Data were analyzed using nonlinear mixed effects models that sought a relati

SUBMITTER: Douglas C 

PROVIDER: S-EPMC11883507 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature