Dynamics in the <i>Phytophthora capsici</i> Effector AVR3a11 Confirm the Core WY Domain Fold.

ABSTRACT: Oomycete pathogens cause large economic losses in agriculture through diseases such as late blight (Phytophthora infestans), and stem and root rot of soybean (Phytophthora sojae). The effector protein AVR3a, from P. infestans, and its homologue AVR3a11 from Phytophthora capsici, are host-translocated effectors that interact with plant proteins to evade defense mechanisms and enable infection. Both proteins belong to the family of RXLR effectors and contain an N-terminal secretion signal, an RXLR motif for translocation into the host cell, and a C-terminal effector domain. Within this family, many proteins have been predicted to contain one or more WY domains as their effector domain, which is proposed to encompass a conserved minimal core fold containing three h

SUBMITTER: Tolchard J 

PROVIDER: S-EPMC11883810 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature