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Occupational Diesel Exposure and Brain Tumors: A Systematic Review and Meta-Analysis.


ABSTRACT: Diesel exhaust (DE) is recognized as a carcinogen for the lungs, although evidence linking it to adult brain tumors is limited. We aimed to systematically review the evidence regarding the association between occupational DE exposure and adult brain and other central nervous system (CNS) tumors. A systematic literature review was conducted to identify cohort studies on occupational DE exposure and the risk of adult cancers other than lung cancer. We meta-analyzed relative risks (RRs) and 95% confidence intervals (CIs) for brain or CNS tumors using the DerSimonian and Laird random-effects model. Fourteen studies were included in the meta-analysis. The results showed no in-creased risk of brain or CNS tumors among workers exposed to DE (RR: 0.99; 95% CI: 0.91, 1.07). Findings were consistent

SUBMITTER: Sassano M 

PROVIDER: S-EPMC11883839 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature