Associations between maternal body composition in the second trimester and premature rupture of membranes: a retrospective study using hospital information system data.

ABSTRACT:

Background

Maternal nutrition is associated with premature rupture of membranes (PROM), which affects 6.7-10.0% of term pregnancies and poses significant health challenges for both mothers and children. However, the relationship between body composition, a detailed reflection of maternal nutrition, and PROM remains under-explored.

Methods

We conducted a retrospective correlational study using data from 38,610 obstetric cases (PROM = 9,857; non-PROM = 28,753) in the hospital information system of West China Second University Hospital. Multi-variable binary logistic regression was performed to investigate the relationships between key body composition indicators and PROM.

Results

Advanced maternal age (OR:1.026, P < 0.001) and nulliparity (OR:1.402, P < 0.001) were asso

SUBMITTER: Liao S 

PROVIDER: S-EPMC11883932 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature