Incidence of acute kidney injury-associated mortality in hospitalized children: a systematic review and meta-analysis.

ABSTRACT:

Background

Acute kidney injury (AKI) is a significant health concern in hospitalized children and is associated with increased mortality. However, the true burden of AKI-associated mortality in pediatric populations remains unclear.

Objective

To determine the pooled incidence of mortality independently associated with AKI in hospitalized children globally.

Data sources

Medline and Embase were searched for studies published by March 2024.

Study eligibility criteria

The inclusion criteria encompassed observational studies involving hospitalized pediatric patients (< 18 years old) with AKI. Only studies that identified AKI as an independent risk factor for increased mortality in multivariate analysis were considered.

Study appraisal and synthesis methods

St

SUBMITTER: Zarei H 

PROVIDER: S-EPMC11883935 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature