Engineered multifunctional nanoparticles for enhanced radiation therapy: three-in-one approach for cancer treatment.

ABSTRACT: Clinical cancer treatment modalities include radiation as one of the first-line therapies used for treating almost two-thirds of cancer patients. Combinational therapy for cancer is becoming extremely popular, with multiple therapies and their pharmacological effects expected to provide a synergistic outcome. The nanotechnology-based combinational therapeutic approach is emerging as a more effective strategy, for its advantages include simultaneous loading of multiple drugs, on-demand drug delivery controlled by external or internal stimulus, targeting a particular site, and the potential to combine physical treatment modalities (like radiation, thermal therapies, etc.) with chemical interventions (like chemotherapy, immunotherapy, etc.). We report a combination of radiotherapy and chemoth

SUBMITTER: Appidi T 

PROVIDER: S-EPMC11883980 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature