Association of uric acid to high-density lipoprotein cholesterol ratio with the presence or absence of hypertensive kidney function: results from the China Health and Retirement Longitudinal Study (CHARLS).

ABSTRACT:

Objective

Some studies have shown that uric acid (UA) to high-density lipoprotein (HDL-C) ratio (UHR), as an indicator of inflammation, is associated with metabolic syndrome and hypertension, but its relationship with decreased renal function is unclear. This study intends to analyze the relationship between UHR and decline in renal function.

Methods

Data were obtained from the 2011-2015 data of the China Health and Aging Tracking Survey (CHARLS) of Peking University, and 7,198 study participants were included and followed up until 2015. The eGFR (Total glomerular filtration rate) was estimated according to the CKD-EPI [1] creatinine equation. eGFR ≥ 60mL/min/1.73 m² at baseline renal function was defined as normal renal function, and eGFR < 60mL/min/1.73 m² at baseline rena

SUBMITTER: Li S 

PROVIDER: S-EPMC11884189 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature