Dynamic changes in neuron-specific enolase level to glasgow coma scale score ratio predict long-term neurological function of diffuse axonal injury patients.

ABSTRACT:

Background

Patients with diffuse axonal injury (DAI) are often plagued by sequelae, and the current indicators for predicting long-term neurological function are not accurate enough. Our previous studies have found that serum Neuron-specific enolase (NSE) level to Glasgow Coma Scale (GCS) score ratio(NGR) at admission could be used as an independent predictor of DAI.

Objective

To explore the accuracy of dynamic changes of NGR in predicting long-term neurological function in patients with DAI.

Methods

Patients with DAI were included based on clinical MRI as the diagnostic standard, and divided into two groups with favorable and unfavorable outcome according to the 6-month Extended Glasgow Outcome Scale (GOSE) as the prognosis indicator. The differences in clinical para

SUBMITTER: Chen W 

PROVIDER: S-EPMC11884207 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature