Plasmon-Driven Gold Nanopillar Multiarrayed Gene Amplification Methodology for the High-Throughput Discrimination of Pathogens.

ABSTRACT: Molecular diagnosis limitations, including complex treatment processes, low cost-effectiveness, and operator-dependent low reproducibility, interrupt the timely prevention of disease spread and the development of medical devices for home and outdoor uses. A newly fabricated gold nanopillar array-based film is presented for superior photothermal energy conversion. Magnifying the metal film surface-to-volume ratio increases the photothermal energy conversion efficiency, resulting in a swift reduction in the gene amplification reaction time. Plasmonic energy-based ultrafast gene amplification and facile confirmation methodology offer a rapid disease discrimination platform for high-throughput multiplexed diagnosis. The superior performance of the gold nanopillar arrayed film is demonstrated b

SUBMITTER: Seo SE 

PROVIDER: S-EPMC11884620 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature