Lesion and lesion network localization of dysnomia after epilepsy surgery.

ABSTRACT: Temporal lobe epilepsy surgery is an effective treatment option for patients with drug-resistant epilepsy. However, neurosurgery poses a risk for cognitive deficits-up to one-third of patients have a decline in naming ability following temporal lobe surgery. In this study, we aimed to better understand the neural correlates associated with reduced naming performance after temporal lobe surgery, with the goal of informing surgical planning strategies to mitigate the risk of dysnomia. We retrospectively identified 85 patients who underwent temporal lobe resective surgery (49 left temporal lobe, 36 right temporal lobe) for whom naming ability was assessed before and >3 months post-surgery using the Boston Naming Test. We used multivariate lesion-symptom mapping to identify resection sites ass

SUBMITTER: Mhanna A 

PROVIDER: S-EPMC11884675 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature