Risk of type 2 diabetes after breast cancer treatment: a population-based cohort study in Denmark.

ABSTRACT:

Purpose

Data on type 2 diabetes (T2D) risk after breast cancer (BC) could guide preventive strategies. Yet, studies had limitations regarding sample size, follow-up, and contemporary treatments. We evaluated the risk of T2D after BC overall, by cancer treatment, and compared with a matched cohort of cancer-free women.

Methods

We assembled a population-based cohort of early-stage BC patients aged 30 years or more diagnosed during 1996-2021 in Denmark. We created a comparison cohort of 5 cancer- and T2D-free women for each BC patient, matched 6 months after BC diagnosis date on age and region. We followed both cohorts until T2D diagnosis, emigration, death, or December 31, 2022. We computed 5-year cumulative incidences and used Cox models to calculate time-varying adjusted haz

SUBMITTER: Kjærgaard KA 

PROVIDER: S-EPMC11884854 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature