Effects of <i>Astragalus membranaceus</i> Leaf Extract on Allergic Inflammation in Immune Cell Lines.

ABSTRACT: Astragalus membranaceus is a perennial plant belonging to the Fabaceae family that is widely distributed across northern Asia. A. membranaceus roots have been used as a traditional medicinal herb because of their numerous health benefits. However, the physiological properties of A. membranaceus leaves remain unknown. During allergic reactions, chemical mediators are released from mast cells, which trigger immediate hypersensitivity and subsequent macrophage-mediated inflammation. In the present study, we investigated the inhibitory effects of A. membranaceus leaf extract (AMLE) on allergic and inflammatory responses in immune cell lines. The results showed that AMLE suppressed the release of histamine and leukotriene B₄ from stimulated mast cells duri

SUBMITTER: Bunddulam P 

PROVIDER: S-EPMC11884941 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature