Systematic review of interventions in early pregnancy among pregnant individuals at risk for hyperglycemia.

ABSTRACT:

Objective

The maternal metabolic environment in early pregnancy can influence fetal growth trajectories. Our objective was to identify interventions initiated in early pregnancy (<20 weeks gestation) in pregnant individuals with risk factors for hyperglycemia and report their impact on primary (neonatal adiposity, small for gestational age, large for gestational age, macrosomia) and secondary outcomes (gestational weight gain, maternal hypertensive disorder, birth injury, NICU admission, preterm delivery, emergency cesarean section).

Data sources

We searched Cochrane Central database, Medline, Embase, CINAHL databases, and clinicaltrials.gov (September 2024) for clinical trials published between 2009 and 2024. Search terms included the key words "early OR during" OR "first t

SUBMITTER: Calancie L 

PROVIDER: S-EPMC11885049 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature