MiniMed 780G system performance in older users with type 1 diabetes: Real-world evidence and the case for stricter glycaemic targets.

ABSTRACT:

Aims

Large-scale studies on the effectiveness of automated insulin delivery (AID) systems in older people with type 1 diabetes are still limited. A multinational, retrospective, real-world study was conducted to examine the performance of the MiniMed™ 780G advanced hybrid closed-loop system in users with type 1 diabetes aged ≥56 years compared with those aged 16-55 years.

Materials and methods

Data from 35 366 MiniMed™ 780G system users aged 16-55 years and 7415 users aged ≥56 years were included. The main outcome was time in range 70-180 mg/dL (TIR); other continuous glucose monitoring (CGM) metrics were also assessed.

Results

Across all users, mean TIR was 77.1% for users aged ≥56 years and 73.1% for those aged 16-55 years (Δ4.0, 95% confidence interval [CI]: 3.8-4.

SUBMITTER: Smaniotto V 

PROVIDER: S-EPMC11885105 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature