Inverse association between atherogenic index of plasma and testosterone in US adult males: A large cross-sectional study from the NAHNES 2011-2016.

ABSTRACT:

Background and objectives

The atherogenic index of plasma (AIP), defined as log10 (triglycerides/high-density lipoprotein cholesterol), serves as a biomarker for atherosclerosis and cardiovascular disease (CVD). It is also associated with conditions such as type 2 diabetes, insulin resistance, depression, and both cardiovascular and overall mortality. Serum lipids have been proven to influence serum testosterone levels, and AIP is a significant marker of lipid levels. We hypothesize that AIP may have a specific relationship with testosterone. This article aims to evaluate the correlation between AIP and total testosterone (TT), as well as testosterone deficiency (TD), among the U.S. population.

Methods

Data were collected from the National Health and Nutrition Examination Su

SUBMITTER: Li T 

PROVIDER: S-EPMC11885243 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature