Imaging characteristics of pediatric primary thymic lymphoepithelioma-like carcinoma: case reports of four children with a literature review.

ABSTRACT:

Objective

This study aimed to analyze the imaging characteristics of lymphoepithelioma-like carcinoma (LELC) in children's thymi.

Methods

Four pediatric cases of primary thymic LELC confirmed by needle biopsy pathology from our research center were enrolled. All children underwent an enhanced chest computed tomography (CT) examination. In addition, 11 cases of pediatric thymic LELC with CT manifestations reported in the literature over the past 20 years were combined to explore their imaging characteristics.

Results

In our research center, there were four cases, all boys, with an average age of 11.25 ± 2.87 years. CT showed a soft tissue mass in the anterior mediastinum in all four cases, with the mass being lobulated or roughly circular and growing laterally. The lar

SUBMITTER: Zhu XD 

PROVIDER: S-EPMC11885277 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature