Relationship between systemic immune response index (SIRI) and COPD: a cross-sectional study based on NHANES 2007-2012.

ABSTRACT: Although the link between inflammation and chronic obstructive pulmonary disease (COPD) is increasingly recognized, the correlation between systemic immune response index (SIRI), a novel marker of inflammation, and COPD is unknown. This cross-sectional study used data from patients with complete lung function in NHANES 2007-2012 to explore the relationship between SIRI and COPD. We performed a series of statistical analyses on a total of 5056 participants, including multiple linear regression, smoothed curve fitting, ROC curve analysis, and subgroup analysis. In the fully corrected model, the logistic multiple regression showed that SIRI was associated with a high risk of COPD (OR1.350, 95% CI:1.220,1.493). The ROC curve showed that SIRI (AUC = 0.596) was significantly more efficient than

SUBMITTER: Jia S 

PROVIDER: S-EPMC11885421 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature