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Unpacking excessive polypharmacy patterns among individuals living with chronic pain in Quebec: a longitudinal study.


ABSTRACT:

Introduction

Excessive polypharmacy, which can be defined as the concurrent use of ≥10 medications, is prevalent among individuals with chronic pain. However, it remains unclear how it may vary between individuals or over time.

Objectives

This study aimed to describe and identify factors associated with trajectories of excessive polypharmacy.

Methods

A retrospective longitudinal study was conducted using the TorSaDE Cohort, which links Canadian Community Health Surveys (2007-2016) and Quebec health administrative databases. Among 9,156 adults living with chronic pain and covered by public prescribed drug insurance, the presence of excessive polypharmacy (yes/no) was assessed monthly for one-year post-survey completion (12 time points). Group-based trajectory modelling

SUBMITTER: De Clifford-Faugere G 

PROVIDER: S-EPMC11885514 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature