Xylitol bioproduction by Candida tropicalis: effects of glucose/xylose ratio and pH on fermentation and gene expression.

ABSTRACT: Xylitol is a highly demanded polyol in the food, pharmaceutical, and chemical industries. However, its current production methods are considered energy-intensive, require the use of hazardous chemical catalysts, and depend on complex and costly equipment. The biotechnological route of xylitol production is proposed as a sustainable alternative, but it still requires process improvements, such as enhanced fermentation capabilities, to be economically competitive. This study examined Candida tropicalis yeast to improve xylose-to-xylitol conversion via glucose: xylose ratio and pH modulation. Key parameters evaluated included xylose consumption rate (r_S), xylose-to-xylitol yield (Y_P/S), and xylitol volumetric productivity (Q_P). Conditions with 50 g/L xylose at

SUBMITTER: Queiroz SS 

PROVIDER: S-EPMC11885737 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature