Shorter telomere length as a prognostic marker for survival and recurrence in breast cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Telomere length is a potential prognostic biomarker in breast cancer, but its clinical utility remains uncertain due to inconsistent findings across the literature. This systematic review and meta-analysis aims to evaluate the association between telomere length and breast cancer survival outcomes, including overall survival (OS), disease-specific survival (DSS), disease-free survival (DFS), and recurrence-free survival (RFS).

Methods

A systematic search of ten sources, including databases and publishers (JSTOR, Nature, ProQuest, PubMed, Sage Journals, ScienceDirect, Science, Scopus, Springer, and Wiley) was conducted to identify studies published up to December 31, 2023. Studies reporting associations between telomere length and survival outcomes in breast cancer

SUBMITTER: Sasmita DMA 

PROVIDER: S-EPMC11886381 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature