Surfactant-Driven Effects on the Antifungal Activity of <i>Lippia origanoides</i> Kunth Essential Oil Encapsulated in Lipid-Based Nanosystems.

ABSTRACT: In recent decades, the recurrence and mortality rates of fungal infections have increased, likely due to antifungal resistance and insufficient attention from healthcare authorities. This trend highlights the urgent need for new antifungal treatments, with essential oils (EOs) emerging as promising alternatives. This study focuses on the characterization, nanoencapsulation, and evaluation of the EO of Lippia origanoides Kunth - pepper-rosemary - on toxicity and antifungal activity against filamentous fungi and yeasts, with a particular emphasis on the influence of surfactants. The EO was characterized by GC-MS and encapsulated in Nanostructured Lipid Carriers (NLCs) using either a nonionic surfactant or a combination with a cationic surfactant. NLCs were further characterized by the

SUBMITTER: Gil GA 

PROVIDER: S-EPMC11886426 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature