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A Versatile Fabrication Route for Screening of Block Copolymer Membranes in Bioprocessing.


ABSTRACT: Traditional poly(ether sulfone) (PES) filters, widely used for sterile, viral, and ultrafiltration, often exhibit restrictions in their selectivity-permeability profile due to their heterogeneous pore size distribution. This limitation has sparked interest in developing novel isoporous membrane materials and fabrication techniques. Among promising candidates, block copolymer (BCP) membranes produced via self-assembly and nonsolvent-induced phase separation (SNIPS) offer significant advantages, including tunable pore size, narrow pore size distribution, high porosity, and enhanced mechanical flexibility. However, optimizing the structure formation in SNIPS remains a complex and time-consuming process, making it unsuitable for rapidly screening new BCP candidates. In response, this study int

SUBMITTER: Meng K 

PROVIDER: S-EPMC11886646 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature