Intentional Weight Loss, Waist Circumference Reduction, and Mortality Risk Among Postmenopausal Women.

ABSTRACT:

Importance

Research investigating weight loss and mortality risk often fails to differentiate between intentional and unintentional weight loss and typically uses body mass index (BMI) as the measure of excess body weight.

Objective

To evaluate associations between weight loss and waist circumference (WC) reduction and mortality, considering weight loss intentionality.

Design, setting, and participants

This cohort study used data from the Women's Health Initiative Observational Study, which had a prospective cohort with mean follow-up of 18.6 years ending in February 2023. The study included women aged 50 to 79 years at 40 clinical centers in the US. Women with missing data, cancer at baseline, or considered underweight at baseline were excluded. Data were collected f

SUBMITTER: Hendryx M 

PROVIDER: S-EPMC11886725 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature