Infective Endocarditis Caused by Non-HACEK Gram-Negative Bacteria, a Registry-Based Comparative Study.

ABSTRACT:

Background

Infective endocarditis (IE) caused by non-HACEK gram-negative bacteria (nHGNB) is uncommon. In the 2023 Duke-ISCVID diagnostic criteria, Pseudomonas aeruginosa and Serratia marcescens were added as "typical" pathogens. We examine the consequences of this addition, the risk of IE in bacteremia from nHGNB species, and the features of IE caused by nHGNB.

Methods

nHGNB IE cases reported to the Swedish Registry of Infective Endocarditis (SRIE) between 2008 and 2023 were identified. Episodes of bacteremia caused by nHGNB during the same period in Region Skåne were used as controls. Characteristics of IE caused by nHGNB were compared with those of other pathogens reported to the SRIE.

Results

One hundred fourteen episodes of nHGNB IE, of which 98 (87

SUBMITTER: Al Janabi J 

PROVIDER: S-EPMC11886782 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature