Evaluating Clinical and Sociodemographic Risk for Symptom Burden Associated Interference With Daily Functioning in the Primary Brain Tumor Patient Population.

ABSTRACT:

Introduction

Symptom burden associated with interference in daily functioning is worse in those with progression or higher-grade glial tumors. This exploratory study aims to identify factors associated with its severity in a diverse cross-sectional cohort of 566 brain tumor patients enrolled in a natural history study (NCT03251989, PI: T.S. Armstrong).

Methods

Sociodemographic and clinical data and self-reported activity-related interference (work, general activity, walking), mood-related interference (relations with others, enjoyment of life, mood) were reported via the MD Anderson Symptom Inventory-Brain Tumor. Activity and mood-related interference mean scores ≥ 2 were categorized as moderate-severe. Logistic regression assessed univariate associations with moderate-sever

SUBMITTER: McIver BA 

PROVIDER: S-EPMC11886885 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature