Survival scenarios of patients with localized and metastatic pancreatic adenocarcinoma: A population-based study.

ABSTRACT: Pancreatic adenocarcinoma (PAC) is notorious for its poor survival. The provision of survival scenarios-that is, best-case, typical and worst-case scenarios-could prove valuable to patients and clinicians. This study investigated survival scenarios and how these have changed over a period of 16 years for patients with PAC. Data from the Netherlands Cancer Registry were used to identify patients with localized and metastatic PAC (2005-2021). Survival scenarios, including best-case, upper-typical, typical (median), lower-typical, and worst-case, were estimated based on survival curve percentiles (p10, p25, p50, p75, and p90). Annual differences were assessed for significance using weighted linear regression analyses. Factors associated with these scenarios were identified through univariable

SUBMITTER: Kuijper SC 

PROVIDER: S-EPMC11887001 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature